Trans-Scleral Controlled-Release of Drugs for Cataract Surgery
نویسندگان
چکیده
Anselmo G. De Oliveira1, José A. Cardillo2,3, Fernando Paganelli2,3, Acácio A. S. Lima-Filho2 and Arnóbio A. Da Silva-Júnior4 1State of Sao Paulo University-UNESP, School of Pharmaceutical Sciences, Department of Pharmaceutics, Araraquara, SP, 2Federal University of Sao Paulo-UNIFESP, Department of Ophthalmology, São Paulo, SP, 3Eye Hospital of Araraquara, Rua Padre Duarte, Araraquara, SP, 4Federal University of Rio Grande do Norte-UFRN, Health Sciences Centre, Natal, RN, Brazil
منابع مشابه
Gelatin Microspheres for the Controlled Release of All-trans-Retinoic Acid Topical Formulation and Drug Delivery Evaluation
A topical o/w cream containing tretinoin microspheres was prepared. Gelatin microspheres of tretinoin were prepared using coacervation method. These microspheres contained about 50% w/w tretinoin. The particle size range of microspheres was between 90-150 m m. In vitro drug release from microspheres and a cream formulation was studied. It was shown that drug release from microspheres followed H...
متن کاملDesign and Evaluation of Ocular Controlled Delivery System for Diclofenac Sodium
Diclofenac sodium as ophthalmic dosage form is used in patients treatment of eye pain, swelling and redness recovering from cataract surgery but it faces the bioavailability limitation of eye drops due to effective protective mechanisms and corneal barrier functions in the eyes. Therefore, this investigation was aimed to develop ocular film formulations to achieve controlled drug release. Drug ...
متن کاملDesign and Evaluation of Ocular Controlled Delivery System for Diclofenac Sodium
Diclofenac sodium as ophthalmic dosage form is used in patients treatment of eye pain, swelling and redness recovering from cataract surgery but it faces the bioavailability limitation of eye drops due to effective protective mechanisms and corneal barrier functions in the eyes. Therefore, this investigation was aimed to develop ocular film formulations to achieve controlled drug release. Drug ...
متن کاملGelatin Microspheres for the Controlled Release of All-trans-Retinoic Acid Topical Formulation and Drug Delivery Evaluation
A topical o/w cream containing tretinoin microspheres was prepared. Gelatin microspheres of tretinoin were prepared using coacervation method. These microspheres contained about 50% w/w tretinoin. The particle size range of microspheres was between 90-150 m m. In vitro drug release from microspheres and a cream formulation was studied. It was shown that drug release from microspheres followed H...
متن کاملImplantation of scleral-sutured posterior chamber intraocular lenses during penetrating keratoplasty.
PURPOSE To evaluate the clinical outcome in 29 patients (29 eyes) who underwent penetrating keratoplasty and scleral-fixation of an intraocular lens. METHODS The indications for penetrating keratoplasty with scleral-fixation of an intraocular lens were anterior chamber pseudophakic corneal edema, aphakic corneal edema, trauma, and corneal scars. Patients with pseudophakic corneal edema underw...
متن کامل